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LAE

High antimicrobial activity, innocuous to humans

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Antimicrobial

LAE® is effective against bacteria, yeast, and molds

LAE® (Ethyl lauroyl arginate hydrochloride or Ethyl lauroyl arginate HCl) is an effective antimicrobial preservative in a wide range of food and cosmetic products. It is able to disrupt the integrity of the cell membrane of these microorganisms.

“The antimicrobial activity of surfactants is a direct consequence of their chemical properties. These properties include reduction of surface tension and the formation of ionic aggregates, which in turn lead to changes in conductivity and solubility of solutions. These surfactants may degrade or solubilize cell membranes at concentrations even below critical micellar concentration, leading to loses of membrane potential, altering cell permeability and leaking of ions and cell constituents. The results of these alterations are metabolic inhibition, growth arrest or cell lysis (Kanazawa et al. 1995). Monohydrochloride of L-arginine, Na-lauroyl ethylester (LAE) is a cationic preservative (Infante et al. 1984). It is derived from lauric acid and arginine. The preparation and application of this product is described in Spanish patent application ES 512643 A1 (Garcı´a Domı´nguez et al. 1983) and European Patent applications (Urgell and Seguer 2003a,b,c).” You can read the complete article here: (J. Appl. Microbiol., 2004, 96 (5) 903-912). Efficacy shown throughout MIC values (Minimum Inhibitory Concentration).

LAE® is active for instance:

• against Gram-positive and Gram-negative bacteria MIC values are between 8 and 64 μg/ml as an average

• and against yeast and mold are between 16 and 128 μg/ml

Please consult the tables that show the MIC values of LAE® against different types of microorganisms, also pathogens. These tables will give an insight into LAE® ‘s wide range of activity and great effectiveness.

LAE® is an antimicrobial food and cosmetic preservative. 

You can also have a look into this success case of LAE® ‘s activity against Listeria monocytogenes. And learn how it has been proved that LAE® is active against this bacteria in several tests as well as in its application in continuous production processes.

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